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Chlorogenic acid has antibacterial, anti-inflammatory, cholagogic, increase white blood cells, scavenging free radicals and other medicinal values, and is an important component of a variety of antibacterial and antiviral drugs. Because its molecular structure contains phenolic hydroxyl, unsaturated double bond, ester bond and other structures, it is easy to hydrolysis, oxidation and other reactions in the process of extraction, preparation and storage, especially leading to the quality instability problems such as the content of chlorogenic acid preparation agent is not up to standard.

Cyclodextrins are cyclic compounds composed of 6-12 D-glucose units linked by α-1, 4-glycosidic bonds. The inner cavity is hydrophobic, and the outer part is hydrophilic due to the aggregation of hydroxyl groups. This unique amphiphilic structure enables cyclodextrins as "host" to encompass different hydrophobic "guest" compounds. Under suitable conditions, ethylenediamine - beta - cyclodextrin inclusion rate than beta cyclodextrin, hydroxypropyl - beta - cyclodextrin inclusion rate is high, the reason is great ethylenediamine - beta - cyclodextrin is better than the other two kinds of cyclodextrin derivatives of water-soluble, and molecules with the structure of amino and carboxyl of the chlorogenic acid molecules structure can be bonded, form chemical bonds that may be more stable. In combination with the chemical environment in human body, ethylenediamine -β -cyclodextrin-chlorogenic acid inclusion complex may better solve the instability and solubility of chlorogenic acid.

Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. specializes in providing cyclodextrin reagents, reagents up to more than 30 kinds, please feel free to call us at 0086 543-2616568.