NEWS

Hydroxypropyl Beta Cyclodextrin(HP-β-CD) is a good pharmaceutical auxiliary material with broad development prospects. It is not only a high water solvent (75g/100 mL), stable to heat and non-toxic to kidney, and almost no stimulation to muscle and mucosa. HP-β-CD can not only increase drug solubility and speed of dissolution, but also improve drug bioavailability and stability.To this end, we encsulated coix seed oil with HP-β-CD to improve its solubility, stability and bioavailability.

The dissolution problem of oil drugs has always been the focus of the research and development of traditional Chinese medicine preparations.At present, researchers have done a lot of work to improve the solubility and bioavailability of drugs, and the use of package compound for inclusion is one of the very effective means.Due to its excellent envelope sealing capacity and biocompatibility, HP-β-CD has a great potential and prospect in the development of traditional Chinese medicine preparations. HP-β-CD has obtained FDA certification in the United States, for intravenous injection and has corresponding products. It is produced by Shandong Binzhou Zhiyuan Biotechnology has research ed its nature, preparation process, stability, pharmacology, toxicity, teratogenesis, mutagenesis, cancer, hemolysis and stimulation. It is a high-tech enterprise focusing on its research, development, production and application, which has positive significance for the development and modernization of TCM preparations.