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Application Of Hydroxypropyl Beta Cyclodextrin In Sirolimus Dispersible Tablets
Time:2020/11/28
Class:NEWS

With the continuous development of organ transplantation, numerous immunosuppressive agents such as cyclosporine, tacrolimus, and mycophenolate mofetil can significantly reduce the incidence of acute rejection, and the long-term survival rate of transplanted organs is also significant. improve. However, the development of efficient, low-toxic immunosuppressants remains one of the focuses of drug research. As a new immunosuppressive agent, Sirolomus has high-efficiency, low-toxic properties. The sirolimus dispersible tablet is convenient to take, has good absorption, and has less gastrointestinal irritation. It is especially suitable for the elderly and those with dysphagia. The drug has little loss during the whole absorption process of the human body; due to the addition of a drug with better disintegration performance The auxiliary material hydroxypropyl beta cyclodextrin has the characteristics of good stability, rapid disintegration and dissolution in water, formation of uniform suspension, high bioavailability, simple preparation process, no special requirements for equipment, suitable for large-scale production.


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