NEWS

Qinxiang Qingjie Oral Liquid is made of 12 traditional Chinese medicines, including Scutellaria baicalensis, Patchouli, and Cicada slough. The patchouli herbs in the prescription contain volatile oil, which is the active ingredient of Qinxiang Qingjie Oral Liquid. Using Tween 80 to dissolve volatile oil to form a preparation, the prepared oral liquid has a strong odor, poor taste, and poor patient compliance. How to solve this problem has become an urgent task for researchers.

Hydroxypropyl betadex is a derivative of beta-cyclodextrin, which not only has excellent inclusion effect, but also has the characteristics of high water solubility, good safety, and improved volatile oil stability. The hydroxypropyl betacyclodextrin and the volatile oil are prepared into an inclusion liquid, and the antiviral oral liquid is prepared with the medicinal liquid according to the prescription amount and the auxiliary materials can not only increase the stability of the volatile oil, but also can obviously improve the mouthfeel of the oral liquid. When the ratio of volatile oil to hydroxypropyl betadex was 1:15, the utilization rate of volatile oil was higher, and the inclusion effect was the best.

Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. specializes in the production of cyclodextrin, among which hydroxypropyl betadex and Betadex sulfobutyl ether sodium have obtained DMF record number,please feel free to contact us at zhiyuan@cydextrin.com.