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Betadex sulfobutyl ether sodium
Time:2023/06/02
Class:NEWS

Betadex sulfobutyl ether sodium also known as Sulfobutyl Ether beta cyclodextrin Sodium salt, also known as Betadex sulfobutyl ether sodium, is an anionic high water soluble cyclodextrin derivative, can form a noncovalent complex with drug molecules, so as to improve drug stability, water soluble, safety, reduce renal toxicity, moderate drug hemolysis, control drug release rate, hide bad odor, etc.It can be used for injection medicine, oral medicine, nasal medicine and eye medicine, and has special affinity and inclusion for nitrogen-containing drugs.

 

It is mainly used in remdesivir injection, remdesivir , a nucleoside analog with antiviral activity, EC50 values for SARS-CoV and MERS-CoV was 74 nM in HAE cells and EC50 for murine hepatitis virus was 30 nM in murine brain tumor cells.

 

On May 7,2020, Japan approved remdesivir, developed by Gilead Technology, as the first COVID-19 treatment drug in China, and will be used for the treatment of severe patients.On October 22,2020, the US Food and Drug Administration (FDA) approved Gilead Science's antiviral drug Reddesivir to treat hospitalized patients with COVID-19, becoming the first officially approved COVID-19 treatment drug in the United States.

 

Wisdom source biological Betadex sulfobutyl ether sodium CDE registration number F20190000285, has been through the association audit site audit to Europe, America, Japan, Korea, India, Pakistan, South America, the Middle East and other countries and regions, through the Pfizer, Johnson & Johnson, geead science, sound pharmaceutical, pearl pharmaceutical group and other domestic and foreign pharmaceutical companies audit and won great recognition and praise!

 

5.Sulfobutyl-Ether-Beta-Cyclodextrin-Sodium-Salt.j