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Betadex Sulfobutyl Ether Sodium is actively expanding production and supply, and global new drug research and development
Time:2020/11/28
Class:NEWS

In the past six months, Xinguan epidemic has spread rapidly all over the world. The epidemic has pushed the "pause" button for human social exchanges and global economic development. However, risks and opportunities always coexist. In every turmoil, some people will fall down, but there must be some people standing up and looking for opportunities in the crisis, which is our best counterattack against the epidemic.

On May 1, U.S. local time, FDA authorized the emergency use of the antiviral drug, remdesivir, for the treatment of severe covid-19 adults and children. Although there are limited data on the efficacy and safety of the drug, a study has shown that radcivir can significantly shorten the recovery time of patients, the FDA said. Japan's Ministry of labor, welfare and welfare said it was ready to put the drug into the rapid approval channel, and it is expected to let domestic patients use the drug one week after Gilead submitted its application.

According to the EUA authorization of FDA, redcivir can be used for critically ill patients. In the United States, severe cases are defined as oxygen saturation (SPO 2) ≤ 94% under indoor air conditions or oxygen support, mechanical ventilation and extracorporeal pulmonary membrane oxygenation (ECMO). Gilead science is expanding the supply of the antiviral drug radcivir, which has just been approved by the FDA for emergency use (EUA), this week for new crown patients in U.S. hospitals. Radcivir has to be given intravenously.

Sulfobutyl beta cyclodextrin sodium produced by Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. is a key excipient for the production of radcivir. As an excipient supplier recognized by pharmaceutical manufacturers at home and abroad, our company is striving to overcome various difficulties and actively cooperate with the R & D and production work of relevant units.

Sulfobutyl beta cyclodextrin sodium is a kind of sodium salt which is alkylated by 1,4-butanesulfonic acid lactone under alkaline condition. It is an anionic and high water soluble derivative of betahydrocyclodextrin. Sulfobutyl beta cyclodextrin sodium can form a non covalent complex with drug molecules, which can improve the stability, water solubility and safety of the drug, reduce the nephrotoxicity, alleviate the hemolysis of the drug, control the drug release rate, cover up the bad smell, etc. it is widely used in injection, oral medicine, nasal medicine, eye medication, external use, external use and inhalation administration Medicine provides a beneficial environment protection and is a new type of pharmaceutical excipients with a very broad application prospect.


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